ADME

Problems with absorption, distribution, metabolism and excretion (ADME) of promising drug candidate may lead to compound failure in clinical trials. To help to resolve these issues Selvita offers a comprehensive ADME platform supporting drug discovery projects from hit to preclinical candidate.

Selvita offer covers wide range of laboratory assays: solubility and permeability tests, metabolic stability of substances, antibiotic properties of substances, and toxicity tests. The data from these studies can select compounds for further development and validate results from other test systems.

Our goal is to substantially increase research productivity, while decreasing labor-based expenses. Our cost-effective approach allows to provide this superior level of quality at prices that are attractive in any global market. Range of our services within the ADME testing area, includes:

  • Solubility testing

  • Partition ratio (LogD)

  • Permeability analysis – PAMPA

  • Plasma binding

  • Metabolite profiling

  • CYP inhibition

  • Metabolic stability