Novel Macrocyclic Antagonists of the CGRP Receptor Part 2: Stereochemical Inversion Induces an Unprecedented Binding Mode Find out more
Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species Find out more
Precision-cut lung slices from bleomycin treated animals as a model for testing potential therapies for idiopathic pulmonary fibrosis Find out more
A novel class of fast-acting antimalarial agents: Substituted 15-membered azalides Find out more
Claudins: Beyond Tight Junctions in Human IBD and Murine Models Find out more
Novel Macrocyclic Antagonists of the Calcitonin Gene-Related Peptide Receptor: Design, Realization, and Structural Characterization of Protein–Ligand Complexes Find out more
Biological evaluation of novel bicyclic heteroaromatic benzazole derived acrylonitriles: synthesis, antiproliferative and antibacterial activity Find out more
New naphtho/thienobenzo-triazoles with interconnected anti-inflammatory and cholinesterase inhibitory activity Find out more
Macrolide Inspired Macrocycles as Modulators of the IL-17A/IL-17RA Interaction Find out more
Synthesis, photochemistry and computational study of novel 1,2,3-triazole heterostilbenes: Expressed biological activity of their electrocyclization photoproducts Find out more
Isolation of MDCK cells with low expression of mdr1 gene and their use in membrane permeability screening Find out more
Unprecedented Epimerization of an Azithromycin Analogue: Synthesis, Structure and Biological Activity of 2'-Dehydroxy-5″-Epi-Azithromycin Find out more
Targeting NOX2 via p47/phox-p22/phox Inhibition with Novel Triproline Mimetics Find out more
Role of Fluorination in the Histone Deacetylase 6 (HDAC6) Selectivity of Benzohydroxamate-Based Inhibitors Find out more
Photocatalytic Approach to α,α-Difluoroalkyl Alcohols Find out more
Novel Macrocyclic Antagonists of the Calcitonin Gene-Related Peptide Receptor: Design, Realization, and Structural Characterization of Protein–Ligand Complexes Find out more
New Bicyclic Azalide Macrolides Obtained by Tandem Palladium Catalyzed Allylic Alkylation/Conjugated Addition Reaction Find out more
Mitogenic activity and proliferative effect of a New-developed short acting Insulin analogue Find out more
In Vitro Evaluation of Pharmacological Properties of a New-Developed Short Acting Insulin Analogue Find out more
Does Preservative Content Affect Drug Permeability? The Permeability Analysis in Vitro of 3 Ophthalmic Latanoprost Formulations in a Human Epithelial Cell Culture Model Find out more
Synthesis of Orthogonally Protected 2,6-Diazaspiro[3.5]nonane and 2,6-Diazaspiro[3.4]octane Analogues as Versatile Building Blocks in Medicinal Chemistry Find out more
5-Keto-3-cyano-2,4-diaminothiophenes as selective maternal embryonic leucine zipper kinase inhibitors Find out more
Continuous Flow Chemo-Enzymatic Baeyer–Villiger Oxidation with Superactive and Extra-Stable Enzyme/Carbon Nanotube Catalyst: An Efficient Upgrade from Batch to Flow Find out more
Oxidation reactions of selected functional groups using Oxone® as the source of molecular oxygen Find out more
A versatile method of epoxide formation with the support of peroxy ionic liquids Find out more
New strategies for the synthesis of lactones using peroxymonosulphate salts, ionic liquids and microwave or ultrasound irradiation. Find out more
Rational design, synthesis and biological profiling of new KDM4C inhibitors Find out more
Pharmacokinetic Evaluation of Brain Penetrating Morpholine-3-hydroxy-2-pyridine Oxime as an Antidote for Nerve Agent Poisoning Find out more
Growth, health aspects and histopathology of brown bullhead (Ameiurus nebulosus L.): replacing fishmeal with soybean meal and brewer’s east Find out more
Clarithromycin inhibits autophagy in colorectal cancer by regulating the hERG1 potassium channel interaction with Find out more
Pro-inflammatory effects of extracellular Hsp70 on NCI-H292 human bronchial epithelial cell line Find out more
Preventing lung pathology and mortality in rabbit Staphylococcus aureus pneumonia models with cytotoxin-neutralizing monoclonal IgGs penetrating the epithelial lining fluid Find out more
Precision-cut lung slices from bleomycin treated animals as a model for testing potential therapies for idiopathic pulmonary fibrosis Find out more
Macrolides: Properties, Synthesis and Application Find out more
Lipophilicity and bio-mimetic properties determination of phytoestrogens using ultra-high-performance liquid chromatography Find out more
Effects of extracellular Hsp70 and cigarette smoke on differentiated THP-1 cells and human monocyte-derived macrophages Find out more
Comparative study of polyphenolic composition and anti-inflammatory activity of Thymus species Find out more
Association of NLRP1 Coding Polymorphism with Lung Function and Serum IL-1β Concentration in Patients Diagnosed with Chronic Obstructive Pulmonary Disease (COPD) Find out more
Antiinflammatory and antiproliferative activity of naphthoxazole, fused hetero-benzoxazole and bridged benzobicyclic photoproducts Find out more
Aflatoxin production and in vitro toxicity of Aspergilli section Flavi isolated from air samples collected from different environments Find out more
A new screening tool to determine chameleonic properties of macrocycles Find out more
