The poster describes the cost and time-effective Selvita platform for cloning and E. coli expression (which is only one of our platforms for expression).

Selvita’s chemists are adept at designing enhanced approaches to target molecules and in this poster and paper illustrate how they collaborated on a synthesis of the atrial fibrillation drug Dronedrone which has been reworked to more than half the number of synthetic steps using efficient and environmentally friendly chemistry.

Selvita has an ongoing commitment to expand chemistry technology to facilitate efficient access to intermediates and final compounds. One such technique which has been developed at Selvita is the application of flow chemistry techniques in synthesis.   In the linked poster Selvita scientists have described a flow chemistry approach to recycle the “waste’ isomer product from a non-enantiospecific primary amine synthesis, offering a means to enhance the yield of desired isomer in synthesis of drugs such as Cinacalcet and Rivastigimine.