Our science

Throughout 13 years of Selvita operations, we’ve had the opportunity to execute a variety of exciting and complex projects for our Clients.
The nature of our business is based on high degree of trust and confidentiality, however we are always very excited to co-author or contribute to scientific publications which present our work.

Whenever possible we publish and present materials such as journal publications, posters, case studies or technical notes, aiming to show the scope of experience of our scientific team.
In the section below, you can find the continuously updated information on our recent publications.

Our science

Blog

Go to blog

Case studies

More case studies

Presentations

Go to presentations

Poster presentations

Poster icon
07 July 2020 Cloning and Expression Platform for Production of Recombinant Proteins
The poster describes the cost and time-effective Selvita platform for cloning and E. coli expression (which is only one of our platforms for expression).
Download presentation
If the download doesn't start automatically in a few seconds, please click here.
Poster icon
07 July 2020 A short synthesis of Dronedarone
Selvita’s chemists are adept at designing enhanced approaches to target molecules and in this poster and paper illustrate how they collaborated on a synthesis of the atrial fibrillation drug Dronedrone which has been reworked to more than half the number of synthetic steps using efficient and environmentally friendly chemistry.
Download presentation
If the download doesn't start automatically in a few seconds, please click here.
Poster icon
07 July 2020 A new competitive strategy for the industrial synthesis of drugs based on chiral amines via utilizing the waste isomer by flow chemistry
Selvita has an ongoing commitment to expand chemistry technology to facilitate efficient access to intermediates and final compounds. One such technique which has been developed at Selvita is the application of flow chemistry techniques in synthesis.   In the linked poster Selvita scientists have described a flow chemistry approach to recycle the “waste’ isomer product from a non-enantiospecific primary amine synthesis, offering a means to enhance the yield of desired isomer in synthesis of drugs such as Cinacalcet and Rivastigimine.
Download presentation
If the download doesn't start automatically in a few seconds, please click here.
Go to poster presentations

Publications

Poster icon
Mitogenic activity and proliferative effect of a New-developed short acting Insulin analogue Human insulin analogues with modified amino acid sequence may exert stronger proliferative effect and carcinogenic potential than insulin itself. The objective of the study was to assess mitogenic activity and activation of proliferation in tumorigenic and non-tumorigenic cell lines upon stimulation with a new-developed short-acting B28Lys-B29Pro human insulin (KP) in comparison to EU Pharmacopeia human insulin standard (HIS) and insulin AspB10 with strong mitogenic, cancerogenic activity. Find out more
Go to publications

Technical notes

Recombinant Stable Cell Line Development

The generation of cell lines overexpressing particular proteins on which drug discovery programs are often based, is necessary for assay development in screening campaigns using initial target-based identification of hit compounds. Recombinant stable cell lines are also used for toxicity studies and general in vitro testing.

Methods to be used and the cell background for the generation of a cell line could depend on several factors: i) the complexity of protein (e.g. dimensions, carrying antibiotic resistance, presence of tags etc.)…

Find out more
Go to technical notes

Contact form

According to the Regulation 2016/679 of the European Parliament and the Council (EU) of 27 April 2016 on the protection of natural persons with regard to the processing of personal data and on the free movement of such data, and repealing Directive 95/46/EC (General Data Protection Regulation; "GDPR"), we hereby inform you that Your personal data will be processed by Selvita S.A. and the companies operating within the Selvita Capital Group in order to present You the Selvita Newsletter. Your personal data are processed in connection with Newsletter subscription and in order to keep You informed about all events taking place in Selvita Capital Group.

We guarantee full transparency of the data processing and compliance with all the rights referred to in GDPR, i.e. the right of access, rectification and deletion of data, limiting data processing, the right to transfer, the right to raise objection against processing. Notwithstanding the above, You have the right to submit a complaint to the supervisory authority. Your personal data are not being subject to automated decision-making, including profiling. Your personal data are provided on the voluntary basis, however please be informed that lack of consent results in inability to provide You the Newsletter by Selvita Group. Your data will be processed for the duration of your consent, unless your consent to the processing of your personal data is revoked. Your consent may be withdrawn at any time by sending a request to the e-mail address: gdpr@selvita.com.

For more information on how Selvita handles personal data please visit: Privacy Policy. I hereby express my consent to the processing of my personal data by Selvita S.A. with registered office in Cracow 30-348, Bobrzyńskiego 14 and its affiliated companies in order to receive the Newsletter, information about events organized by the Selvita Capital Group and other information regarding Selvita Group activity in accordance with the Regulation 2016/679 of the European Parliament and the Council (EU) of 27 April 2016 on the protection of natural persons with regard to the processing of personal data and on the free movement of such data, and repealing Directive 95/46/EC (General Data Protection Regulation).